Lamp1溶酶体
TīmeklisLAMP2. Lysosome-associated membrane protein 2 ( LAMP2 ), also known as CD107b ( C luster of D ifferentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins . The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides … Tīmeklis2024. gada 18. jūl. · LAMP1 (lysosomal associated membrane protein 1) and LAMP2 are distributed among autophagic and endolysosomal organelles. Despite widespread distribution, LAMP1 is routinely used as a lysosome marker and LAMP1-positive organelles are often referred to as lysosomal compartments.
Lamp1溶酶体
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LAMP2 has been specifically implicated in tumor cell metastasis. Both LAMP1 and LAMP2 have been found expressed on the surface of cancerous tumors, specifically in cells of highly metastatic cancer such as colon cancer and melanoma. They are rarely found on the plasma membranes of normal cells, and are found more on highly metastatic tumors than on poorly metastatic ones. LAMP2, along with LAMP1, interact with E-selectin and galectins to mediate the adhesion of so… TīmeklisLAMP1 Antibody (MA1-164) in ICC/IF. Immunofluorescence analysis of LAMP1 (Lysosome-associated membrane glycoprotein 1) was performed using 80% confluent log phase L6 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for …
TīmeklisLAMP-1 Antibody (H4A3) is an IgG 1 κ mouse monoclonal LAMP-1 antibody (also designated LAMP1 antibody or CD107a antibody) that detects the LAMP-1 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM. LAMP-1 Antibody (H4A3) is available as both the non-conjugated anti-LAMP-1 antibody form, as well as … Tīmeklis2008. gada 23. sept. · Lysosomal membrane glycoprotein which plays an important role in lysosome biogenesis, autophagy, and cholesterol homeostasis ( By similarity ). Also plays an important role in NK-cells cytotoxicity ( PubMed: 23632890, PubMed: 2024921 ). Mechanistically, participates in cytotoxic granule movement to the cell surface and …
Tīmeklis尽管分布广泛，但LAMP1通常用作溶酶体标记物，而LAMP1阳性细胞器通常称为溶酶体区室。通过应用免疫电子显微镜（iTEM）和共聚焦成像与Airyscan显微镜相结合， … TīmeklisMilana Fraiberg, Zvulun Elazar, in Progress in Molecular Biology and Translational Science, 2024. 3.4 LAMP2. The LAMP2 gene is located on the Xq24 chromosome. Lysosome-associated membrane protein-2 (LAMP2), together with LAMP1, comprises a major protein component of lysosomal membranes.LAMP2 is a type I …
TīmeklisFor LAMP1 immunostaining, cells were fixed with 100% methanol for 8 min. Cells were incubated with various primary antibodies at 4°C overnight. The primary antibodies used in this study included anti-TFEB (Cell Signaling Technology, 4240), anti-TFE3 (Sigma-Aldrich, HPA023881), anti-LAMP1 (Abcam, ab24170), and anti-NFE2L2/NRF2 …
TīmeklisAnti-LAMP1 antibody - Lysosome Marker (ab24170) at 1/700 dilution (in 5% milk for 4 hours at 20°C) + Rat Kidney - whole tissue lysate at 18 µg Secondary An HRP … differences between india and pakistanTīmeklislamp1质量控制：＞95%(还原性sds-page) lamp1制剂：冻干品 lamp1保存： 冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。 复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。 lamp1复溶： 打开试剂管前请先离心。 复溶浓度推荐大于100μg/ml。 format for financial statementsTīmeklisAntibodies that detect LAMP1 (CD107a) can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunocytochemistry, Immunohistochemistry and Immunoprecipitation. These antibodies target LAMP1 (CD107a) in Human, Mouse, Rat, Non-human primate and Hamster samples. differences between individualsTīmeklis2013. gada 6. jūn. · LAMP1 is required for efficient delivery of perforin, but not granzyme B, to lytic granules. (A) YTS cells, transduced with CTRL or LAMP1 RNAi, were homogenized and fractionated on a continuous 0% to 30% gradient of iodoxanol. The presence of the indicated proteins in the gradient fractions was assessed by … format for genealogy bookTīmeklis溶酶体相关膜蛋白 1 和 2（LAMP1 和 LAMP2）是两种含量丰富的溶酶体膜蛋白 (1,2)。. 两者都是跨膜蛋白，并且在溶酶体的内腔面氨基末端被高度糖基化，这能保护蛋白质不被水解 (3)。. LAMP1 蛋白羧基末端暴露在细胞浆中，同时它含有一个将 LAMP 蛋白靶向至 … format for father of the bride speechhttp://www.bjbalb.com/html/Recombinant-Protein/JN1133.html format for formal letter class 7Tīmeklis溶酶体是膜结合细胞器，含有降解生物分子的酶，可降解碳水化合物、脂类、核酸和多肽等等 [ 1–3 ]。 细胞内分子的消化过程称为 自噬 ，而通过内吞进入细胞内的胞外物质 … differences between indian curries