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WebMay 14, 2024 · Blood pressure medications, like alpha-blockers and nitrates, work to increase blood flow and lower the patient’s blood pressure. Because phosphodiesterase inhibitors also dilate the blood vessels and increase blood flow, taking these medications in conjunction with alpha-blockers and nitrates can lead to a dangerous drop in blood … WebAug 29, 2024 · The recommended starting dose for Cialis intended for once daily use is 2.5mg, take at the same time each day, without regard to timing of sexual activity. This may be increased to 5mg/day based on need and tolerability. May be taken with or without food. Cialis is available as a generic, under the name tadalafil. 3. WebAs tadalafil is prescribed to treat PH (pulmonary hypertension), its mechanism is focused on treating this form of high blood pressure. So, this mechanism may not necessarily work … raymond jaeger obituary